TERT-BUTYL 3-(2-(2-HYDROXYETHOXY)ETHOXY)PROPANOATE
Hydroxy-PEG3-t-butylester
CAS: 133803-81-3
Molecular Formula: C11H22O5
TERT-BUTYL 3-(2-(2-HYDROXYETHOXY)ETHOXY)PROPANOATE - Names and Identifiers
TERT-BUTYL 3-(2-(2-HYDROXYETHOXY)ETHOXY)PROPANOATE - Physico-chemical Properties
| Molecular Formula | C11H22O5 |
| Molar Mass | 234.29 |
| Density | 1.046±0.06 g/cm3(Predicted) |
| Boling Point | 321.8±22.0 °C(Predicted) |
| pKa | 14.36±0.10(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Physical and Chemical Properties | Bioactive Hydroxy-PEG2-(CH2)2-Boc is an ADC linker used to synthesize antibody-coupled drugs (ADC). Hydroxy-PEG2-(CH2)2-Boc is derived from patented WO2004008101A2 (compound 196). Hydroxy-PEG2-(CH2)2-Boc can also be used as PROTAC linker for PROTAC synthesis.. |
TERT-BUTYL 3-(2-(2-HYDROXYETHOXY)ETHOXY)PROPANOATE - Upstream Downstream Industry
| Downstream Products | Azido-PEG2-acid |
TERT-BUTYL 3-(2-(2-HYDROXYETHOXY)ETHOXY)PROPANOATE - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 4.268 ml | 21.341 ml | 42.682 ml |
| 5 mM | 0.854 ml | 4.268 ml | 8.536 ml |
| 10 mM | 0.427 ml | 2.134 ml | 4.268 ml |
| 5 mM | 0.085 ml | 0.427 ml | 0.854 ml |
Last Update：2024-01-02 23:10:35
TERT-BUTYL 3-(2-(2-HYDROXYETHOXY)ETHOXY)PROPANOATE - Uses and synthesis methods
Target
Non-cleavable
PEGs
Alkyl/ether
in vitro studies
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Last Update：2024-04-09 21:04:16
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View History
TERT-BUTYL 3-(2-(2-HYDROXYETHOXY)ETHOXY)PROPANOATE
Boc-DL-环丙基甘氨酸
3-(2,5-二氟苯氧基)氮杂环丁烷
756799-99-2
FMOC-4-氟-D-B-苯丙氨酸
四氢-2H-吡喃-2-酮
3-Methyl-2-nitrobenzoate Methyl ester
4-三氟甲基异吲哚啉-1-酮
4-[5-(1H-INDOL-3-YLMETHYLENE)-4-OXO-2-THIOXO-THIAZOLIDIN-3-YL]-BUTYRIC ACID
4-甲氧基苯基乙酸甲酯
Boc-DL-环丙基甘氨酸
3-(2,5-二氟苯氧基)氮杂环丁烷
756799-99-2
FMOC-4-氟-D-B-苯丙氨酸
四氢-2H-吡喃-2-酮
3-Methyl-2-nitrobenzoate Methyl ester
4-三氟甲基异吲哚啉-1-酮
4-[5-(1H-INDOL-3-YLMETHYLENE)-4-OXO-2-THIOXO-THIAZOLIDIN-3-YL]-BUTYRIC ACID
4-甲氧基苯基乙酸甲酯
Downstream Products for TERT-BUTYL 3-(2-(2-HYDROXYETHOXY)ETHOXY)PROPANOATE